100-Point Model

Comparative index of greenness (G-CI)

Score analytical methods against green chemistry principles: ten equally weighted criteria (100 points) with ±2 adjustments, plus G-CI solvent sustainability.

Scoring criteria (100 points)

Select the best match for each criterion.

Criteria 1–5

1. Type of analytical method (10)

2. Extraction technique (10)

3. Pre-steps (synthesis / pretreatment) (10)

4. Sample size (mg or µL) (10)

5. Solvent sustainability (10)

Total score for (Hazard of utilized solvents and reagents × Volume factor)

Criteria 6–10

6. Total waste generated (10)

7. Waste treatment (10)

8. Operator safety & emissions (10)

9. Throughput (samples/h) (10)

10. Automation (10)

Additional adjustments

±2 points per item according to the reference table.

Derivatization required (−2)

Off-site analysis (−2)

Bio-source / plant-based materials (+2)

Optimization (DOE / AQbD) (+2)

Multianalyte or multi-parameter (+2)

Assessment name (optional)

Shown in the combined report. If left blank, “Assessment n” is assigned.

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